3.0
Summary
| Name |  ADIPOR1View Modifications |
| Full Name | Adiponectin receptor protein 1 |
| Synonyms | Progestin and adipoQ receptor family member I | PAQR1, TESBP1A |
| Primary ID | Q96A54 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337). Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | GRK2 | down-regulates quantity by destabilization 
phosphorylation
|
ADIPOR1 | 0.2 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | ADIPOQ | up-regulates 
binding
|
ADIPOR1 | 0.666 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | ADIPOR1 | up-regulates
binding
|
APPL1 | 0.746 |
| Publications: | 1 | Organism: | Homo Sapiens | |