Summary

Name RAB22A
Full Name Ras-related protein Rab-22A
Synonyms Rab-22 | RAB22
Primary ID Q9UL26
Links - -
Type protein
Relations 2
Function Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes (PubMed:16537905). Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth (PubMed:21849477). Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form (PubMed:16537905).

Viewer

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png relocalization BLOC-2 0.2
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding Early Endosome 0.464
Publications: 1 Organism: Homo Sapiens