+ |
ATM | up-regulates
phosphorylation
|
ZNF148 |
0.369 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-155634 |
Ser202 |
GEKPFQCsQCDMRFI |
Homo sapiens |
|
pmid |
sentence |
17560543 |
Here we found that zbp-89 is phosphorylated by atm kinase in vitro and in vivo. Disruption of the atm phosphorylation motif (202)sq within the zinc finger domain of zbp-89 attenuated its ability to enhance p21(waf1) activation by butyrate. Moreover, disruption of the atm phosphorylation site abrogated the ability of zbp-89 to potentiate butyrate induction of endogenous p21(waf1) expression. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
ZNF148 | down-regulates quantity by repression
transcriptional regulation
|
SOX18 |
0.26 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254821 |
|
|
Homo sapiens |
HeLa Cell |
pmid |
sentence |
18496767 |
co-transfection experiments revealed that over-expression of Sp3 and ZBP-89 down-regulate, while over-expression of NF-Y up-regulates SOX18 promoter activity in HeLa cells |
|
Publications: |
1 |
Organism: |
Homo Sapiens |