Summary
Name | PDE10A View Modifications |
Full Name | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A |
Synonyms | PDE10_HUMAN |
Primary ID | Q9Y233 |
Links | - - |
Type | protein |
Relations | 2 |
Inhibitors | PF-2545920 |
Function | Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition. |
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