3.0
Summary
| Name |  CBY1
|
| Full Name | Protein chibby homolog 1 |
| Synonyms | ARPP-binding protein, Cytosolic leucine-rich protein, PIGEA-14, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 | ARB1, C22orf2, CBY, PGEA1 |
| Primary ID | Q9Y3M2 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. |
binding