3.0
Summary
| Name |  GRIP1View Modifications |
| Full Name | Glutamate receptor-interacting protein 1 |
| Synonyms | GRIP-1 |
| Primary ID | Q9Y3R0 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons (PubMed:10197531). Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | ERK1/2 | up-regulates activity 
phosphorylation
|
GRIP1 | 0.2 |
| Publications: | 1 | Organism: | In Vitro | |
| + | GRIP1 | up-regulates
binding
|
MEF2C | 0.377 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | GRIP1 | up-regulates activity
binding
|
KIF5C | 0.33 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Brain | |||
| + | GRIP1 | up-regulates activity
binding
|
GRIPAP1 | 0.524 |
| Publications: | 1 | Organism: | Rattus Norvegicus | |