| + |
ARRB2 | up-regulates 
binding
|
KIF3A |
0.623 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-148773 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16908539 |
We demonstrate that _-arrestins mediate the activity-dependent interaction of smo and the kinesin motor protein kif3a. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-199107 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23074268 |
Betaarrestin 2 was subsequentialy shown to bridge smo to the kinestesin motor kif3 to promote ciliary accumulation of smo in mammalian cells |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
KIF3A | up-regulates 
|
Plus-end directed sliding movement |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272531 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19773780 |
In general, N-kinesins and C-kinesins drive microtubule plus end- and minus end-directed motilities, respectively, and M-kinesins depolymerize microtubules1,9 (Box 1).|Forty-five genes that encode kinesin superfamily proteins (also known as KIFs) have been discovered in the mouse and human genomes.|KIFs are molecular motors that directionally transport various cargos, including membranous organelles, protein complexes and mRNAs, along the microtubule system. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KIF3A | up-regulates
|
Minus-end directed microtubule movement |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272538 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19773780 |
In general, N-kinesins and C-kinesins drive microtubule plus end- and minus end-directed motilities, respectively, and M-kinesins depolymerize microtubules1,9 (Box 1).|Forty-five genes that encode kinesin superfamily proteins (also known as KIFs) have been discovered in the mouse and human genomes.|KIFs are molecular motors that directionally transport various cargos, including membranous organelles, protein complexes and mRNAs, along the microtubule system. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ARRB1 | up-regulates
binding
|
KIF3A |
0.532 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-178672 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18497258 |
Kif3a is essential for shh-mediated signaling in mammalian systems (5), and we identified kif3a as a arr1 binding partner in a proteomics screen (18). To test whether arrs, smo, and kif3a might work in concert. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
AP3B1 | up-regulates activity
binding
|
KIF3A |
0.378 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260398 |
|
|
Mus musculus |
MEF Cell |
| pmid |
sentence |
| 19934039 |
Here, we show that the beta subunit of AP-3, a clathrin-associated protein complex required for HIV-1 release, is a target of IP(7)-mediated pyrophosphorylation. We have identified Kif3A, a motor protein of the kinesin superfamily, as an AP3B1-binding partner and demonstrate that Kif3A, like the AP-3 complex, is involved in an intracellular process required for HIV-1 Gag release. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
3.0
KIF3A
- 
- 