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Summary
Name
KLK4
Full Name
Kallikrein-4
Synonyms
Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Prostase, Serine protease 17 | EMSP1, PRSS17, PSTS
Primary ID
Q9Y5K2
Links
-
-
Type
protein
Relations
1
Function
Has a major role in enamel formation (PubMed:15235027). Required during the maturation stage of tooth development for clearance of enamel proteins and normal structural patterning of the crystalline matrix (By similarity).
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by mechanism
none
transcriptional regulation
by effect
none
up-regulates quantity by expression
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
T-47D cell
Relations
Regulator
Mechanism
target
score
ℹ
+
PGR
up-regulates quantity by expression
transcriptional regulation
KLK4
0.261
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-254913
Homo sapiens
T-47D Cell
pmid
sentence
19147544
we have shown that K4.pPRE interacts directly with the PR to up-regulate KLK4 gene expression in T47D cells.
Publications:
1
Organism:
Homo Sapiens