Summary

Name CLIC4
Full Name Chloride intracellular channel protein 4
Synonyms Intracellular chloride ion channel protein p64H1 |
Primary ID Q9Y696
Links - -
Type protein
Relations 1
Function Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates quantity by stabilization img/direct-activation.png phosphorylation CLIC4 0.2
Publications: 1 Organism: Homo Sapiens