Summary

Name CACNG2
Full Name Voltage-dependent calcium channel gamma-2 subunit
Synonyms Neuronal voltage-gated calcium channel gamma-2 subunit, Transmembrane AMPAR regulatory protein gamma-2, TARP gamma-2
Primary ID Q9Y698
Links - -
Type protein
Relations 1
Function Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation CACNG2 0.418
Publications: 1 Organism: Chlorocebus Aethiops