| + |
LE-TGN SNARE | up-regulates activity 
relocalization
|
IGF2R |
0.51 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253083 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18195106 |
These findings place the retromer complex upstream of both STX10 function and the GCC185 tethering complex in MPR transport. Together, our data suggest that STX10, STX16, Vti1a, and VAMP3 are important for the trafficking of both CD- and CI-MPRs.|Thus, MPRs must pass through a compartment of pH ≤ 5.5 before returning to the Golgi to carry out their biological function. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
STX10 | form complex 
binding
|
LE-TGN SNARE |
0.774 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253080 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 18195106 |
We show in human cells that a soluble NSF attachment protein receptor (SNARE) complex comprised of syntaxin 10 (STX10), STX16, Vti1a, and VAMP3 is required for this MPR transport |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
STX16 | form complex
binding
|
LE-TGN SNARE |
0.815 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253079 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 18195106 |
We show in human cells that a soluble NSF attachment protein receptor (SNARE) complex comprised of syntaxin 10 (STX10), STX16, Vti1a, and VAMP3 is required for this MPR transport |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
LE-TGN SNARE | up-regulates activity
relocalization
|
M6PR |
0.557 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253084 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18195106 |
These findings place the retromer complex upstream of both STX10 function and the GCC185 tethering complex in MPR transport. Together, our data suggest that STX10, STX16, Vti1a, and VAMP3 are important for the trafficking of both CD- and CI-MPRs.|Thus, MPRs must pass through a compartment of pH ≤ 5.5 before returning to the Golgi to carry out their biological function. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
VAMP3 | form complex
binding
|
LE-TGN SNARE |
0.739 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253082 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 18195106 |
We show in human cells that a soluble NSF attachment protein receptor (SNARE) complex comprised of syntaxin 10 (STX10), STX16, Vti1a, and VAMP3 is required for this MPR transport |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
VTI1A | form complex
binding
|
LE-TGN SNARE |
0.82 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253081 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 18195106 |
We show in human cells that a soluble NSF attachment protein receptor (SNARE) complex comprised of syntaxin 10 (STX10), STX16, Vti1a, and VAMP3 is required for this MPR transport |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
LE-TGN SNARE