| + |
SDHA | form complex 
binding
|
Mitochondrial respiratory chain complex II |
0.95 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262188 |
|
|
|
|
| pmid |
sentence |
| 30030361 |
Complex II (EC 1.3.5.1) or succinate dehydrogenase (quinone) is shared between the TCA cycle and the ETC and has no proton pumping activity. It is composed of four nDNA-encoded subunits. The two hydrophilic catalytic subunits are SDHA/SDH1 and SDHB/SDH2. Hydrophobic subunits SDHC/SDH3 and SDHD/SDH4 constitute the cII membrane anchor, containing a haem b group and two CoQ binding sites |
|
| Publications: |
1 |
| + |
Inner_mitochondrial_membrane | up-regulates 
relocalization
|
Mitochondrial respiratory chain complex II |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267006 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 25627476 |
One of the main functions of the IMM is the housing of proteins that make up the electron transport chain (ETC) which ultimately produces ATP. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SDHD | form complex
binding
|
Mitochondrial respiratory chain complex II |
0.924 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262187 |
|
|
|
|
| pmid |
sentence |
| 30030361 |
Complex II (EC 1.3.5.1) or succinate dehydrogenase (quinone) is shared between the TCA cycle and the ETC and has no proton pumping activity. It is composed of four nDNA-encoded subunits. The two hydrophilic catalytic subunits are SDHA/SDH1 and SDHB/SDH2. Hydrophobic subunits SDHC/SDH3 and SDHD/SDH4 constitute the cII membrane anchor, containing a haem b group and two CoQ binding sites |
|
| Publications: |
1 |
| + |
SDHB | form complex
binding
|
Mitochondrial respiratory chain complex II |
0.965 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262189 |
|
|
|
|
| pmid |
sentence |
| 30030361 |
Complex II (EC 1.3.5.1) or succinate dehydrogenase (quinone) is shared between the TCA cycle and the ETC and has no proton pumping activity. It is composed of four nDNA-encoded subunits. The two hydrophilic catalytic subunits are SDHA/SDH1 and SDHB/SDH2. Hydrophobic subunits SDHC/SDH3 and SDHD/SDH4 constitute the cII membrane anchor, containing a haem b group and two CoQ binding sites |
|
| Publications: |
1 |
| + |
iron-sulfur cluster | up-regulates activity
chemical activation
|
Mitochondrial respiratory chain complex II |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262136 |
|
|
|
|
| pmid |
sentence |
| 26083061 |
Respiratory chain complexes I–III depend on Fe-S clusters for function |
|
| Publications: |
1 |
| + |
Mitochondrial respiratory chain complex II | up-regulates 
|
Respiratory electron transport chain |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262138 |
|
|
|
|
| pmid |
sentence |
| 30030361 |
The oxidative phosphorylation system (OXPHOS) of the mitochondrial inner membrane is composed of five enzymes (complexes I–V; cI–V). In mammals, they are all multimeric and, except for cII, have subunits encoded both in the mitochondrial genome (mtDNA) and the nuclear genome (nDNA). |
|
| Publications: |
1 |
| + |
SDHC | form complex
binding
|
Mitochondrial respiratory chain complex II |
0.953 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262186 |
|
|
|
|
| pmid |
sentence |
| 30030361 |
Complex II (EC 1.3.5.1) or succinate dehydrogenase (quinone) is shared between the TCA cycle and the ETC and has no proton pumping activity. It is composed of four nDNA-encoded subunits. The two hydrophilic catalytic subunits are SDHA/SDH1 and SDHB/SDH2. Hydrophobic subunits SDHC/SDH3 and SDHD/SDH4 constitute the cII membrane anchor, containing a haem b group and two CoQ binding sites |
|
| Publications: |
1 |
3.0
Mitochondrial respiratory chain complex II
CPX-561