| + |
SMC5/6 | up-regulates 
|
DNA_repair |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265487 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27427983 |
The SMC5/6 complex, consisting of SMC5, SMC6, and non-SMC elements NSMCE1–6, has key roles in the maintenance of chromosome integrity during mitotic proliferation, meiosis, and DNA repair and is critical for genome stability. In particular, the SMC5/6 complex is involved in resolving intermediates during recombination (5, 6) and other complex DNA structures, such as stalled replication forks |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SMC5 | form complex 
binding
|
SMC5/6 |
0.891 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265481 |
|
|
in vitro |
|
| pmid |
sentence |
| 27427983 |
The SMC5/6 complex, consisting of SMC5, SMC6, and non-SMC elements NSMCE1–6, has key roles in the maintenance of chromosome integrity during mitotic proliferation, meiosis, and DNA repair and is critical for genome stability. In particular, the SMC5/6 complex is involved in resolving intermediates during recombination (5, 6) and other complex DNA structures, such as stalled replication forks |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
NSMCE4A | form complex
binding
|
SMC5/6 |
0.826 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265486 |
|
|
in vitro |
|
| pmid |
sentence |
| 27427983 |
The SMC5/6 complex, consisting of SMC5, SMC6, and non-SMC elements NSMCE1–6, has key roles in the maintenance of chromosome integrity during mitotic proliferation, meiosis, and DNA repair and is critical for genome stability. In particular, the SMC5/6 complex is involved in resolving intermediates during recombination (5, 6) and other complex DNA structures, such as stalled replication forks |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
NSMCE2 | form complex
binding
|
SMC5/6 |
0.879 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265484 |
|
|
in vitro |
|
| pmid |
sentence |
| 27427983 |
The SMC5/6 complex, consisting of SMC5, SMC6, and non-SMC elements NSMCE1–6, has key roles in the maintenance of chromosome integrity during mitotic proliferation, meiosis, and DNA repair and is critical for genome stability. In particular, the SMC5/6 complex is involved in resolving intermediates during recombination (5, 6) and other complex DNA structures, such as stalled replication forks |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
NSMCE1 | form complex
binding
|
SMC5/6 |
0.873 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265483 |
|
|
in vitro |
|
| pmid |
sentence |
| 27427983 |
The SMC5/6 complex, consisting of SMC5, SMC6, and non-SMC elements NSMCE1–6, has key roles in the maintenance of chromosome integrity during mitotic proliferation, meiosis, and DNA repair and is critical for genome stability. In particular, the SMC5/6 complex is involved in resolving intermediates during recombination (5, 6) and other complex DNA structures, such as stalled replication forks |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
SMC6 | form complex
binding
|
SMC5/6 |
0.896 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265482 |
|
|
in vitro |
|
| pmid |
sentence |
| 27427983 |
The SMC5/6 complex, consisting of SMC5, SMC6, and non-SMC elements NSMCE1–6, has key roles in the maintenance of chromosome integrity during mitotic proliferation, meiosis, and DNA repair and is critical for genome stability. In particular, the SMC5/6 complex is involved in resolving intermediates during recombination (5, 6) and other complex DNA structures, such as stalled replication forks |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
NSMCE3 | form complex
binding
|
SMC5/6 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265485 |
|
|
in vitro |
|
| pmid |
sentence |
| 27427983 |
The SMC5/6 complex, consisting of SMC5, SMC6, and non-SMC elements NSMCE1–6, has key roles in the maintenance of chromosome integrity during mitotic proliferation, meiosis, and DNA repair and is critical for genome stability. In particular, the SMC5/6 complex is involved in resolving intermediates during recombination (5, 6) and other complex DNA structures, such as stalled replication forks |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
SMC5/6 | up-regulates
|
Chromosome_segregation |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265488 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27427983 |
The SMC5/6 complex, consisting of SMC5, SMC6, and non-SMC elements NSMCE1–6, has key roles in the maintenance of chromosome integrity during mitotic proliferation, meiosis, and DNA repair and is critical for genome stability. In particular, the SMC5/6 complex is involved in resolving intermediates during recombination (5, 6) and other complex DNA structures, such as stalled replication forks |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
SMC5/6
CPX-6086