| + |
ADNP | form complex 
binding
|
ChAHP |
0.3 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266751 |
|
|
Mus musculus |
HM-1 ES Cell |
| pmid |
sentence |
| 29795351 |
Here we show that ADNP interacts with the chromatin remodeller CHD4 and the chromatin architectural protein HP1 to form a stable complex, which we refer to as ChAHP. Besides mediating complex assembly, ADNP recognizes DNA motifs that specify binding of ChAHP to euchromatin. we have discovered ChAHP, a gene-regulatory complex that consists of the chromatin remodeller CHD4, the DNA-binding factor ADNP, and the heterochromatin proteins HP1β and HP1γ. By locally restricting access to DNA, ChAHP prevents endodermal gene transcription in mouse ES cells and during neuroectodermal differentiation. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
CBX1 | form complex
binding
|
ChAHP |
0.366 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266754 |
|
|
Mus musculus |
HM-1 ES Cell |
| pmid |
sentence |
| 29795351 |
Here we show that ADNP interacts with the chromatin remodeller CHD4 and the chromatin architectural protein HP1 to form a stable complex, which we refer to as ChAHP. Besides mediating complex assembly, ADNP recognizes DNA motifs that specify binding of ChAHP to euchromatin. In conclusion, CHD4, ADNP and HP1β/γ form a stable protein complex, which we refer to as ChAHP. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
CBX3 | form complex
binding
|
ChAHP |
0.416 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266753 |
|
|
Mus musculus |
HM-1 ES Cell |
| pmid |
sentence |
| 29795351 |
Here we show that ADNP interacts with the chromatin remodeller CHD4 and the chromatin architectural protein HP1 to form a stable complex, which we refer to as ChAHP. Besides mediating complex assembly, ADNP recognizes DNA motifs that specify binding of ChAHP to euchromatin. In conclusion, CHD4, ADNP and HP1β/γ form a stable protein complex, which we refer to as ChAHP. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
CHD4 | form complex
binding
|
ChAHP |
0.421 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266752 |
|
|
Mus musculus |
HM-1 ES Cell |
| pmid |
sentence |
| 29795351 |
Here we show that ADNP interacts with the chromatin remodeller CHD4 and the chromatin architectural protein HP1 to form a stable complex, which we refer to as ChAHP. Besides mediating complex assembly, ADNP recognizes DNA motifs that specify binding of ChAHP to euchromatin. In conclusion, CHD4, ADNP and HP1β/γ form a stable protein complex, which we refer to as ChAHP. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
3.0
ChAHP