| + |
TSH | up-regulates activity 
binding
|
TSHR |
0.558 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267048 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 25905363 |
The thyroid-stimulating hormone (TSH) receptor (TSHR) is a member of the glycoprotein hormone receptors (GPHRs), a sub-group of class A G protein-coupled receptors (GPCRs). TSHR and its ligand thyrotropin are of essential importance for growth and function of the thyroid gland. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Thyroid Gland |
| Pathways: | Thyroid Hormone Metabolism |
| + |
CGA | form complex 
binding
|
TSH |
0.665 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267046 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 8196184 |
TSH is a heterodimer composed of common alpha subunit and unique beta subunit encoded by genes located on different chromosomes. It is known that the expression of these subunit genes is regulated in different mechanism by several extracellular factors. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Thyroid Gland |
| Pathways: | Thyroid Hormone Metabolism |
| + |
TSHB | form complex
binding
|
TSH |
0.665 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267047 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 8196184 |
TSH is a heterodimer composed of common alpha subunit and unique beta subunit encoded by genes located on different chromosomes. It is known that the expression of these subunit genes is regulated in different mechanism by several extracellular factors. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Thyroid Gland |
| Pathways: | Thyroid Hormone Metabolism |
3.0
TSH
CPX-6096