| + |
MIS18BP1 | form complex 
binding
|
CENP-A recruiting complex |
0.794 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281033 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 38951710 |
A central player mediating this process is the Mis18 complex (Mis18α, Mis18β and Mis18BP1), which recruits the CENP-A-specific chaperone HJURP to centromeres for CENP-A deposition. Here, using a multi-pronged approach, we characterise the structure of the Mis18 complex and show that multiple hetero- and homo-oligomeric interfaces facilitate the hetero-octameric Mis18 complex assembly composed of 4 Mis18α, 2 Mis18β and 2 Mis18BP1. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
OIP5 | form complex
binding
|
CENP-A recruiting complex |
0.793 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281032 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 38951710 |
A central player mediating this process is the Mis18 complex (Mis18α, Mis18β and Mis18BP1), which recruits the CENP-A-specific chaperone HJURP to centromeres for CENP-A deposition. Here, using a multi-pronged approach, we characterise the structure of the Mis18 complex and show that multiple hetero- and homo-oligomeric interfaces facilitate the hetero-octameric Mis18 complex assembly composed of 4 Mis18α, 2 Mis18β and 2 Mis18BP1. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MIS18A | form complex
binding
|
CENP-A recruiting complex |
0.751 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281034 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 38951710 |
A central player mediating this process is the Mis18 complex (Mis18α, Mis18β and Mis18BP1), which recruits the CENP-A-specific chaperone HJURP to centromeres for CENP-A deposition. Here, using a multi-pronged approach, we characterise the structure of the Mis18 complex and show that multiple hetero- and homo-oligomeric interfaces facilitate the hetero-octameric Mis18 complex assembly composed of 4 Mis18α, 2 Mis18β and 2 Mis18BP1. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CENP-A recruiting complex | up-regulates activity 
binding
|
HJURP |
0.638 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281035 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 38951710 |
A central player mediating this process is the Mis18 complex (Mis18α, Mis18β and Mis18BP1), which recruits the CENP-A-specific chaperone HJURP to centromeres for CENP-A deposition. Here, using a multi-pronged approach, we characterise the structure of the Mis18 complex and show that multiple hetero- and homo-oligomeric interfaces facilitate the hetero-octameric Mis18 complex assembly composed of 4 Mis18α, 2 Mis18β and 2 Mis18BP1. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
CENP-A recruiting complex