| + |
CCDC47 | form complex 
binding
|
PAT intramembrane chaperone complex |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281079 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32814900 |
Here we identify the PAT complex, an abundant obligate heterodimer of the widely conserved ER-resident membrane proteins CCDC47 and Asterix. The PAT complex engages nascent TMDs that contain unshielded hydrophilic side chains within the lipid bilayer, and it disengages concomitant with substrate folding. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
WDR83OS | form complex
binding
|
PAT intramembrane chaperone complex |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281080 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32814900 |
Here we identify the PAT complex, an abundant obligate heterodimer of the widely conserved ER-resident membrane proteins CCDC47 and Asterix. The PAT complex engages nascent TMDs that contain unshielded hydrophilic side chains within the lipid bilayer, and it disengages concomitant with substrate folding. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PAT intramembrane chaperone complex | up-regulates 
|
Protein_maturation |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281081 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32814900 |
Here we identify the PAT complex, an abundant obligate heterodimer of the widely conserved ER-resident membrane proteins CCDC47 and Asterix. The PAT complex engages nascent TMDs that contain unshielded hydrophilic side chains within the lipid bilayer, and it disengages concomitant with substrate folding. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PAT intramembrane chaperone complex | up-regulates
|
Protein_insertion_into_membrane |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281082 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32814900 |
Here we identify the PAT complex, an abundant obligate heterodimer of the widely conserved ER-resident membrane proteins CCDC47 and Asterix. The PAT complex engages nascent TMDs that contain unshielded hydrophilic side chains within the lipid bilayer, and it disengages concomitant with substrate folding. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
PAT intramembrane chaperone complex
CPX-7020