| + |
METTL5 | form complex 
binding
|
METTL5-TRM112 methyltransferase complex |
0.356 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281121 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31328227 |
Here, we identify METTL5 as the enzyme responsible for 18S rRNA m6A modification and confirm ZCCHC4 as the 28S rRNA modification enzyme. We show that METTL5 must form a heterodimeric complex with TRMT112, a known methyltransferase activator, to gain metabolic stability in cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TRMT112 | form complex
binding
|
METTL5-TRM112 methyltransferase complex |
0.356 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281122 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31328227 |
Here, we identify METTL5 as the enzyme responsible for 18S rRNA m6A modification and confirm ZCCHC4 as the 28S rRNA modification enzyme. We show that METTL5 must form a heterodimeric complex with TRMT112, a known methyltransferase activator, to gain metabolic stability in cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
METTL5-TRM112 methyltransferase complex | up-regulates 
|
Protein_methylation |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281123 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31328227 |
Here, we identify METTL5 as the enzyme responsible for 18S rRNA m6A modification and confirm ZCCHC4 as the 28S rRNA modification enzyme. We show that METTL5 must form a heterodimeric complex with TRMT112, a known methyltransferase activator, to gain metabolic stability in cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
METTL5-TRM112 methyltransferase complex
CPX-2850