| + |
SLC30A4 | form complex 
binding
|
ZNT2-ZNT4 proton-coupled zinc antiporter complex |
0.329 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281295 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 29048339 |
ZNT transporters function as zinc/proton exchangers [19,20], and can form homodimers or heterodimers. This review outlines the functions of ZNT and ZIP transporters in the regulation and function of secretory pathways, in particular, the early secretory pathway, focusing on several recent aspects of the molecular processes underlying the ER stress response, as well as the activation of zinc-requiring ectoenzymes. Zinc transporters also play important roles in secretory granules/vesicles that contain high amounts of zinc, such as insulin granules, synaptic vesicles, and secretory vesicles involved in milk secretion |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SLC30A2 | form complex
binding
|
ZNT2-ZNT4 proton-coupled zinc antiporter complex |
0.329 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281296 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 29048339 |
ZNT transporters function as zinc/proton exchangers [19,20], and can form homodimers or heterodimers. This review outlines the functions of ZNT and ZIP transporters in the regulation and function of secretory pathways, in particular, the early secretory pathway, focusing on several recent aspects of the molecular processes underlying the ER stress response, as well as the activation of zinc-requiring ectoenzymes. Zinc transporters also play important roles in secretory granules/vesicles that contain high amounts of zinc, such as insulin granules, synaptic vesicles, and secretory vesicles involved in milk secretion |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ZNT2-ZNT4 proton-coupled zinc antiporter complex | up-regulates quantity 
relocalization
|
zinc(2+) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281310 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 29048339 |
ZNT transporters function as zinc/proton exchangers [19,20], and can form homodimers or heterodimers. This review outlines the functions of ZNT and ZIP transporters in the regulation and function of secretory pathways, in particular, the early secretory pathway, focusing on several recent aspects of the molecular processes underlying the ER stress response, as well as the activation of zinc-requiring ectoenzymes. Zinc transporters also play important roles in secretory granules/vesicles that contain high amounts of zinc, such as insulin granules, synaptic vesicles, and secretory vesicles involved in milk secretion |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
ZNT2-ZNT4 proton-coupled zinc antiporter complex