+ |
Chaperone-mediated autophagy | down-regulates quantity by destabilization
|
Hexokinase |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-270269 |
|
|
Homo sapiens |
ES-2 Cell |
pmid |
sentence |
26323688 |
Our proteome analysis revealed that HK2 is a CMA substrate and that its degradation by CMA is regulated by glucose availability. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
HSPA8 | up-regulates activity
|
Chaperone-mediated autophagy |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-259991 |
|
|
in vitro |
|
pmid |
sentence |
2799391 |
A 73-kilodalton (kD) intracellular protein was found to bind to peptide regions that target intracellular proteins for lysosomal degradation in response to serum withdrawal. This protein cross-reacted with a monoclonal antibody raised to a member of the 70-kD heat shock protein (hsp70) family, and sequences of two internal peptides of the 73-kD protein confirm that it is a member of this family. |
|
Publications: |
1 |
Organism: |
In Vitro |
+ |
Chaperone-mediated autophagy | down-regulates quantity by destabilization
|
HK2 |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261247 |
|
|
Homo sapiens |
ES-2 Cell |
pmid |
sentence |
26323688 |
Our proteome analysis revealed that HK2 is a CMA substrate and that its degradation by CMA is regulated by glucose availability. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
LAMP2 | up-regulates activity
|
Chaperone-mediated autophagy |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-259990 |
|
|
Cricetulus griseus |
Ovary Cell Line |
pmid |
sentence |
8662539 |
Here, the lysosomal membrane glycoprotein LGP96 was identified as a receptor for the selective import and degradation of proteins within lysosomes. Specific substrates of this proteolytic pathway bound to the cytosolic tail of a 96-kilodalton lysosomal membrane protein in two different binding assays. |
|
Publications: |
1 |
Organism: |
Cricetulus Griseus |