+ |
CHMP2A | up-regulates
|
Viral_budding |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260844 |
|
|
in vitro |
|
pmid |
sentence |
30989108 |
ESCRT-III has been proposed to assemble inside the membrane neck formed at a late stage of a budding vesicle or an enveloped virus. The membrane neck needs to be constricted to proceed to membrane fission, thereby splitting the vesicle or virus from the cellular membrane. CHMP2A and CHMP3 are engaged late in ESCRT-III assembly, recruit VPS4 (31, 42), and block Snf7 (CHMP4) polymerization |
|
Publications: |
1 |
Organism: |
In Vitro |
+ |
ESCRT-III | up-regulates
|
Viral_budding |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-265534 |
|
|
Homo sapiens |
|
pmid |
sentence |
26775243 |
The ESCRT machinery drives a diverse collection of membrane remodeling events, including multivesicular body biogenesis, release of enveloped retroviruses and both reformation of the nuclear envelope and cytokinetic abscission during mitotic exit. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CHMP3 | up-regulates
|
Viral_budding |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260845 |
|
|
in vitro |
|
pmid |
sentence |
30989108 |
ESCRT-III has been proposed to assemble inside the membrane neck formed at a late stage of a budding vesicle or an enveloped virus. The membrane neck needs to be constricted to proceed to membrane fission, thereby splitting the vesicle or virus from the cellular membrane. CHMP2A and CHMP3 are engaged late in ESCRT-III assembly, recruit VPS4 (31, 42), and block Snf7 (CHMP4) polymerization |
|
Publications: |
1 |
Organism: |
In Vitro |