| + |
BLOC-1 | up-regulates 
|
Melanosome_assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265939 |
|
|
Homo sapiens |
Melanocyte |
| pmid |
sentence |
| 22203680 |
Lysosome-related organelles (LROs) 6 are present in a range of cells in multicellular eukaryotes and include lytic granules, lung lamellar bodies, platelet-dense granules, and melanosomes (1.). The melanosome of the pigment cells in the skin and eye is the best studied of the LROs (1., 2.). The biogenesis of the melanosome and other LROs requires the AP-3 adaptor complex, the class C Vps complex, and three BLOC (biogenesis of lysosome-related organelles complex) complexes |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
AP-3 complex | up-regulates
|
Melanosome_assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265941 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22203680 |
Lysosome-related organelles (LROs) 6 are present in a range of cells in multicellular eukaryotes and include lytic granules, lung lamellar bodies, platelet-dense granules, and melanosomes (1.). The melanosome of the pigment cells in the skin and eye is the best studied of the LROs (1., 2.). The biogenesis of the melanosome and other LROs requires the AP-3 adaptor complex, the class C Vps complex, and three BLOC (biogenesis of lysosome-related organelles complex) complexes |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Neuronal AP-3 | up-regulates
|
Melanosome_assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268522 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22203680 |
Lysosome-related organelles (LROs) 6 are present in a range of cells in multicellular eukaryotes and include lytic granules, lung lamellar bodies, platelet-dense granules, and melanosomes (1.). The melanosome of the pigment cells in the skin and eye is the best studied of the LROs (1., 2.). The biogenesis of the melanosome and other LROs requires the AP-3 adaptor complex, the class C Vps complex, and three BLOC (biogenesis of lysosome-related organelles complex) complexes |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
Melanosome_assembly