| + |
BLOC-1 | up-regulates 
|
Platelet_dense_granule_formation |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265940 |
|
|
Homo sapiens |
Blood Platelet |
| pmid |
sentence |
| 12019270 |
BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules|Interestingly, immunofluorescence and in vitro binding experiments demonstrated that pallidin/BLOC-1 is able to associate with actin filaments. We propose that BLOC-1 mediates the biogenesis of lysosome-related organelles by a mechanism that may involve self-assembly and interaction with the actin cytoskeleton. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
AP-3 complex | up-regulates
|
Platelet_dense_granule_formation |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265942 |
|
|
Homo sapiens |
Blood Platelet |
| pmid |
sentence |
| 12019270 |
BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules|Interestingly, immunofluorescence and in vitro binding experiments demonstrated that pallidin/BLOC-1 is able to associate with actin filaments. We propose that BLOC-1 mediates the biogenesis of lysosome-related organelles by a mechanism that may involve self-assembly and interaction with the actin cytoskeleton. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Neuronal AP-3 | up-regulates
|
Platelet_dense_granule_formation |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268523 |
|
|
Homo sapiens |
Blood Platelet |
| pmid |
sentence |
| 12019270 |
BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules|Interestingly, immunofluorescence and in vitro binding experiments demonstrated that pallidin/BLOC-1 is able to associate with actin filaments. We propose that BLOC-1 mediates the biogenesis of lysosome-related organelles by a mechanism that may involve self-assembly and interaction with the actin cytoskeleton. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
Platelet_dense_granule_formation