| + |
UV stress | up-regulates 
|
KRT14 |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251900 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11875647 |
UVB increases keratin 5 and keratin 14 expression through direct activation of the EGF receptor in SVHK. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UV stress | up-regulates
|
RRM2B |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259362 |
|
|
Homo sapiens |
PC-3 Cell |
| pmid |
sentence |
| 14583450 |
Taken together, we conclude that UV-induced activation of p53R2 transcription and binding of p53R2 to hRRM1 to form RR holoenzyme are impaired in the p53-mutant cell line PC3. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UV stress | up-regulates
|
MAP3K4 |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-226605 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9305639 |
Overexpression of a dominant-negative MTK1 mutant [MTK1(K/R)] strongly inhibited the activation of the p38 pathway by environmental stresses (osmotic shock, UV and anisomycin)[]These results indicate that MTK1 is a major mediator of environmental stresses that activate the p38 MAPK pathway |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | P38 Signaling |
| + |
UV stress | up-regulates
|
CDKN2A |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-252376 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11830546 |
The expression of the melanoma susceptibility gene product p16 is increased after UVR both in epidermally derived cell lines and in human skin. The increased expression of p16 after exposure to suberythemal doses of UVR is potentiated by α-MSH, a ligand for MC1R, and this effect is mimicked by cAMP, the intracellular mediator of α-MSH signaling via the MC1 receptor. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Malignant Melanoma |
3.0
UV stress