Satellite: IFN gamma

Pathway ID: SIGNOR-ScIFNG

Description: IFN gamma is a potent inflammatory cytokine that has important effect on myogenesis in satellite cells. IFN gamma can promote the activation of CIITA (transactivator of MHC class II) through the JAK/STAT pathway. This signaling cascade leads to the inhibition of myogenin and skeletal muscle differentiation.

Curated by: Alessandro Palma

10 Seed Entities

Organism:
Name Primary ID
IFNGR2 P38484
MYOD1 P15172
Skeletal_muscle_differentiation SIGNOR-PH1
CIITA P33076
JAK1 P23458
IFNG P01579
JAK2 O60674
MYOG P15173
STAT1 P42224
IFNGR1 P15260