TNF-alpha Signaling

Pathway ID: SIGNOR-TA View in NDEx

Description: The Tumor necrosis factor modulates a vast array of cell functions including inflammation, apoptosis, cell proliferation, immunity and differentiation. TNF alpha is mainly produced by macrophages.

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26 Seed Entities

Organism:
Name Primary ID
PARP1 P09874
JUN P05412
MAP3K5 Q99683
MAP3K1 Q13233
TRAF2 Q12933
NFKBIA P25963
BAX Q07812
RIPK1 Q13546
TNF P01375
MAP2K3 P46734
IKK-complex SIGNOR-C14
MAP2K7 O14733
NfKb-p65/p50 SIGNOR-C13
Apoptosis SIGNOR-PH2
TNFRSF1A P19438
MAP2K4 P45985
Proliferation SIGNOR-PH4
Inflammation SIGNOR-PH12
CASP8 Q14790
FADD Q13158
MAPK14 Q16539
MAPK8 P45983
BAG4 O95429
CASP3 P42574
TRADD Q15628
BID P55957