Summary

Name BAG4
Full Name BAG family molecular chaperone regulator 4
Synonyms BAG-4, Bcl-2-associated athanogene 4, Silencer of death domains | SODD
Primary ID O95429
Links - -
Type protein
Relations 3
Pathways TNF-alpha Signaling
Function Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria.

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation BAG4 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding TNFRSF1A 0.632
Publications: 1 Organism: Mus Musculus
Pathways:TNF-alpha Signaling
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation BAG4 0.2
Publications: 1 Organism: Homo Sapiens