VEGF Signaling

Pathway ID: SIGNOR-VEGF

Description: From Wikipedia.Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF),[1] is a signal protein produced by cells that stimulates the formation of blood vessels. To be specific, VEGF is a sub-family of growth factors, the platelet-derived growth factor family of cystine-knot growth factors. They are important signaling proteins involved in both vasculogenesis (the de novo formation of the embryonic circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature)

Curated by: Gianni

29 Seed Entities

Organism:
Name Primary ID
CALM1 P0DP23
PRKCA P17252
MEK1/2 SIGNOR-PF25
BAD Q92934
Proliferation SIGNOR-PH4
Vascular_Permeability SIGNOR-PH140
calcium(2+) CHEBI:29108
GRB2 P62993
1D-myo-inositol 1,4,5-trisphosphate CHEBI:16595
PLCG1 P19174
KDR P35968
nitric oxide CHEBI:16480
ERK1/2 SIGNOR-PF1
VEGFA P15692
PI3K SIGNOR-C156
PDPK1 O15530
ITPR1 Q14643
NOS3 P29474
HRAS P01112
VEGFD O43915
SOS1 Q07889
VEGFC P49767
PTK2 Q05397
Cell_migration SIGNOR-PH38
AKT SIGNOR-PF24
1,2-diacyl-sn-glycerol CHEBI:17815
PXN P49023
BRAF P15056
PIP3 CHEBI:16618