4.0
VEGF Signaling
Pathway ID: SIGNOR-VEGF
Description: From Wikipedia.Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF),[1] is a signal protein produced by cells that stimulates the formation of blood vessels. To be specific, VEGF is a sub-family of growth factors, the platelet-derived growth factor family of cystine-knot growth factors. They are important signaling proteins involved in both vasculogenesis (the de novo formation of the embryonic circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature)
Curated by: Gianni
Description: From Wikipedia.Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF),[1] is a signal protein produced by cells that stimulates the formation of blood vessels. To be specific, VEGF is a sub-family of growth factors, the platelet-derived growth factor family of cystine-knot growth factors. They are important signaling proteins involved in both vasculogenesis (the de novo formation of the embryonic circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature)
Curated by: Gianni
29 Seed Entities
Organism: 
|
Name | Primary ID |
|---|---|
| CALM1 | P0DP23 |
| PRKCA | P17252 |
| MEK1/2 | SIGNOR-PF25 |
| BAD | Q92934 |
| Vascular_Permeability | SIGNOR-PH140 |
| GRB2 | P62993 |
| KDR | P35968 |
| nitric oxide | CHEBI:16480 |
| PI3K | SIGNOR-C156 |
| PDPK1 | O15530 |
| VEGFC | P49767 |
| PTK2 | Q05397 |
| Cell_migration | SIGNOR-PH38 |
| BRAF | P15056 |
| PIP3 | CHEBI:16618 |
| Proliferation | SIGNOR-PH4 |
| calcium(2+) | CHEBI:29108 |
| 1D-myo-inositol 1,4,5-trisphosphate | CHEBI:16595 |
| PLCG1 | P19174 |
| ERK1/2 | SIGNOR-PF1 |
| VEGFA | P15692 |
| ITPR1 | Q14643 |
| NOS3 | P29474 |
| HRAS | P01112 |
| VEGFD | O43915 |
| SOS1 | Q07889 |
| AKT | SIGNOR-PF24 |
| 1,2-diacyl-sn-glycerol | CHEBI:17815 |
| PXN | P49023 |