4.0
Summary
| Name |  alvocidib
|
| Synonyms | (-)-cis-5,7-dihydroxy-2-(2-chlorophenyl)-8-(4-(3-hydroxy-1-methyl)piperidinyl)-4H-1-benzopyran-4-one (ChemIDplus), alvocidib (WHO MedNet), alvocidib (WHO MedNet), alvocidib (WHO MedNet), alvocidibum (WHO MedNet), Flavopiridol (ChemIDplus), HMR 1274 (ChemIDplus), HMR-1274 (ChEBI), L 86-8275 (ChemIDplus), L 868275 (ChemIDplus), L-868275 (ChemIDplus), L86-8275 (ChemIDplus) |
| IUPAC | 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one |
| Formula | C21H20ClNO5 |
| PRIMARY ID (Read more) |
CHEBI:47344 |
| Type | chemical |
| Relations | 9 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | alvocidib | down-regulates 
chemical inhibition
|
CDK9 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | alvocidib | down-regulates activity
chemical inhibition
|
CDK2 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | alvocidib | down-regulates
chemical inhibition
|
CDK6 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | alvocidib | down-regulates
chemical inhibition
|
CDK2 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | alvocidib | down-regulates
chemical inhibition
|
CDK1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | alvocidib | down-regulates
chemical inhibition
|
CDK4 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | alvocidib | down-regulates
chemical inhibition
|
CDK7 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | alvocidib | down-regulates
chemical inhibition
|
CDK5 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | alvocidib | down-regulates activity
chemical inhibition
|
CDK4 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |