3.0
Summary
| Name |  CDKL5View Modifications |
| Full Name | Cyclin-dependent kinase-like 5 |
| Synonyms | Serine/threonine-protein kinase 9 | STK9 |
| Primary ID | O76039 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Pathways | Rett syndrome |
| Function | Mediates phosphorylation of MECP2 (PubMed:15917271, PubMed:16935860). May regulate ciliogenesis (PubMed:29420175). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CDKL5 | down-regulates activity 
phosphorylation
|
AMPH | 0.369 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | CDKL5 |
phosphorylation
|
LRRC4C | 0.44 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CDKL5 | up-regulates activity 
phosphorylation
|
CDKL5 | 0.2 |
| Publications: | 2 | Organism: | In Vitro | |
| Pathways: | Rett syndrome | |||
| + | MEF2C | up-regulates quantity by expression 
transcriptional regulation
|
CDKL5 | 0.358 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Pathways: | Rett syndrome | |||
| + | CDKL5 |
phosphorylation
|
MECP2 | 0.621 |
| Publications: | 1 | Organism: | In Vitro | |
| Pathways: | Rett syndrome | |||