Summary

Name GNAI2
Full Name Guanine nucleotide-binding protein G
Synonyms Adenylate cyclase-inhibiting G alpha protein | GNAI2B
Primary ID P04899
Links - -
Type protein
Relations 6
Pathways Sonic Hedgehog
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase

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Relations

Regulator Mechanism target score ℹ
+ SMOup-regulates activity img/direct-activation.png binding GNAI2 0.403
Publications: 2 Organism: Mus Musculus, Homo Sapiens
Pathways:Sonic Hedgehog
+ GNAI2down-regulates activity img/direct_inhibition.png binding ADCY1 0.579
Publications: 1 Organism: Homo Sapiens
Pathways:Sonic Hedgehog
+ GNAI2down-regulates img/direct_inhibition.png binding Adenylate_cyclase 0.618
Publications: 1 Organism: Homo Sapiens
+ GNAI2down-regulates img/direct_inhibition.png binding ADCY1 0.579
Publications: 1 Organism: Homo Sapiens
Pathways:Sonic Hedgehog
+ GNAI2up-regulates activity img/direct-activation.png binding TNFAIP8 0.2
Publications: 1 Organism: Homo Sapiens