Summary

Name IL13
Full Name Interleukin-13
Synonyms IL-13 | NC30
Primary ID P35225
Links - -
Type protein
Relations 3
Pathways FAP: IL4/IL13 induction, Macrophage polarization, Macrophage: IL4, Macrophage: Polarization and myogenesis
Function Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages (By similarity).

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Relations

Regulator Mechanism target score ℹ
+ IL13up-regulates img/direct-activation.png binding IL13RA1 0.853
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle, Lung, Smooth Muscle
+ IL13up-regulates activity img/direct-activation.png binding IL4R 0.896
Publications: 1 Organism: Homo Sapiens
Pathways:Macrophage polarization
+ IL13up-regulates img/direct-activation.png binding IL4R 0.896
Publications: 1 Organism: Homo Sapiens
Pathways:Macrophage polarization