| + |
MAPK9 | down-regulates 
phosphorylation
|
TOB1 |
0.346 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-91067 |
Ser152 |
PASSVSSsPSPPFGH |
Homo sapiens |
|
| pmid |
sentence |
| 12151396 |
Biochemical analyses have then shown that erk mapk (erk2) and jnk/sapk (jnk2) bind to and phosphorylate tob in vitro. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-91071 |
Ser154 |
SSVSSSPsPPFGHSA |
Homo sapiens |
|
| pmid |
sentence |
| 12151396 |
Biochemical analyses have then shown that erk mapk (erk2) and jnk/sapk (jnk2) bind to and phosphorylate tob in vitro. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-88744 |
Ser154 |
SSVSSSPsPPFGHSA |
Homo sapiens |
|
| pmid |
sentence |
| 12050114 |
Biochemical analyses have then shown that erk mapk (erk2) and jnk/sapk (jnk2) bind to and phosphorylate tob in vitro. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-88748 |
Ser164 |
FGHSAAVsPTFMPRS |
Homo sapiens |
|
| pmid |
sentence |
| 12050114 |
Biochemical analyses have then shown that erk mapk (erk2) and jnk/sapk (jnk2) bind to and phosphorylate tob in vitro. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-91075 |
Ser164 |
FGHSAAVsPTFMPRS |
Homo sapiens |
T-lymphocyte |
| pmid |
sentence |
| 12151396 |
Biochemical analyses have then shown that erk mapk (erk2) and jnk/sapk (jnk2) bind to and phosphorylate tob in vitro. |
|
| Publications: |
5 |
Organism: |
Homo Sapiens |
| + |
MAPK3 | down-regulates
phosphorylation
|
TOB1 |
0.36 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-88728 |
Ser152 |
PASSVSSsPSPPFGH |
Homo sapiens |
|
| pmid |
sentence |
| 12050114 |
Biochemical analyses have then shown that erk mapk (erk2) and jnk/sapk (jnk2) bind to and phosphorylate tob in vitro. Erk catalyzes the phosphorylation more efficiently than jnk |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-91059 |
Ser154 |
SSVSSSPsPPFGHSA |
Homo sapiens |
T-lymphocyte |
| pmid |
sentence |
| 12151396 |
Biochemical analyses have then shown that erk mapk (erk2) and jnk/sapk (jnk2) bind to and phosphorylate tob in vitro. Erk catalyzes the phosphorylation more efficiently than jnk |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-88732 |
Ser154 |
SSVSSSPsPPFGHSA |
Homo sapiens |
|
| pmid |
sentence |
| 12050114 |
Tob is rapidly phosphorylated at Ser 152, Ser 154, and Ser 164 by Erk1 and Erk2 upon growth-factor stimulation. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-91063 |
Ser164 |
FGHSAAVsPTFMPRS |
Homo sapiens |
T-lymphocyte |
| pmid |
sentence |
| 12151396 |
Biochemical analyses have then shown that erk mapk (erk2) and jnk/sapk (jnk2) bind to and phosphorylate tob in vitro. Erk catalyzes the phosphorylation more efficiently than jnk |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-88736 |
Ser164 |
FGHSAAVsPTFMPRS |
Homo sapiens |
|
| pmid |
sentence |
| 12050114 |
Biochemical analyses have then shown that erk mapk (erk2) and jnk/sapk (jnk2) bind to and phosphorylate tob in vitro. Erk catalyzes the phosphorylation more efficiently than jnk |
|
| Publications: |
5 |
Organism: |
Homo Sapiens |
| + |
MAPK1 | down-regulates
phosphorylation
|
TOB1 |
0.361 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-88716 |
Ser152 |
PASSVSSsPSPPFGH |
Homo sapiens |
|
| pmid |
sentence |
| 12050114 |
Tob is rapidly phosphorylated at ser 152, ser 154, and ser 164 by erk1 and erk2 upon growth-factor stimulation. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-88720 |
Ser154 |
SSVSSSPsPPFGHSA |
Homo sapiens |
|
| pmid |
sentence |
| 12050114 |
Tob is rapidly phosphorylated at ser 152, ser 154, and ser 164 by erk1 and erk2 upon growth-factor stimulation. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-88724 |
Ser164 |
FGHSAAVsPTFMPRS |
Homo sapiens |
|
| pmid |
sentence |
| 12050114 |
Tob is rapidly phosphorylated at ser 152, ser 154, and ser 164 by erk1 and erk2 upon growth-factor stimulation. |
|
| Publications: |
3 |
Organism: |
Homo Sapiens |
| + |
TOB1 | down-regulates activity
binding
|
CCR4-NOT complex |
0.651 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-273616 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 18377426 |
We found that Tob associates with the CCR4-NOT complex. The carboxyl-terminal half of Tob interacted with Cnot1, a core protein of the CCR4-NOT complex. We further showed that the deadenylase activity associated with the complex was suppressed in vitro by Tob. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ERK1/2 | down-regulates
phosphorylation
|
TOB1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270210 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12050114 |
Tob is rapidly phosphorylated at Ser 152, Ser 154, and Ser 164 by Erk1 and Erk2 upon growth-factor stimulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Gbeta | down-regulates
phosphorylation
|
TOB1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270123 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12050114 |
Tob is rapidly phosphorylated at Ser 152, Ser 154, and Ser 164 by Erk1 and Erk2 upon growth-factor stimulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
TOB1
- 
- 