| + |
VPS13B | up-regulates 
|
Neurite_outgrowth |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266872 |
|
|
Rattus norvegicus |
|
| pmid |
sentence |
| 25492866 |
Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth. COH1 and RAB6 regulate neurite outgrowth in primary neurons |
|
| Publications: |
1 |
Organism: |
Rattus Norvegicus |
| + |
RAB6B | down-regulates activity 
binding
|
VPS13B |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269205 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 25492866 |
Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth. COH1 Golgi Localization Is Mediated by Active RAB6 . COH1 Interacts with All Three Mammalian RAB6 Homologues |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RAB6C | up-regulates activity 
binding
|
VPS13B |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266871 |
|
|
Rattus norvegicus |
Pyramidal Neuron |
| pmid |
sentence |
| 25492866 |
Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth. We show that COH1 forms a physical and functional complex with RAB6. Our results point to a role of COH1 as a RAB6 effector protein. Depletion of COH1 leads to decreased neurite outgrowth in cultured primary hippocampal neurons. These results establish a critical role for RAB6-dependent function of COH1 in neuritogenesis by regulating Golgi complex organization. COH1 Interacts with All Three Mammalian RAB6 Homologues |
|
| Publications: |
1 |
Organism: |
Rattus Norvegicus |
| + |
RAB6C | down-regulates activity
binding
|
VPS13B |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269204 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 25492866 |
Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth. COH1 Golgi Localization Is Mediated by Active RAB6 . COH1 Interacts with All Three Mammalian RAB6 Homologues |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RAB6B | up-regulates activity
binding
|
VPS13B |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266870 |
|
|
Rattus norvegicus |
Pyramidal Neuron |
| pmid |
sentence |
| 25492866 |
Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth. We show that COH1 forms a physical and functional complex with RAB6. Our results point to a role of COH1 as a RAB6 effector protein. Depletion of COH1 leads to decreased neurite outgrowth in cultured primary hippocampal neurons. These results establish a critical role for RAB6-dependent function of COH1 in neuritogenesis by regulating Golgi complex organization. |
|
| Publications: |
1 |
Organism: |
Rattus Norvegicus |
| + |
RAB6A | down-regulates activity
binding
|
VPS13B |
0.381 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269203 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 25492866 |
Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth. COH1 Golgi Localization Is Mediated by Active RAB6 . COH1 Interacts with All Three Mammalian RAB6 Homologues |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RAB6A | up-regulates activity
binding
|
VPS13B |
0.381 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266869 |
|
|
Rattus norvegicus |
Pyramidal Neuron |
| pmid |
sentence |
| 25492866 |
Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth. We show that COH1 forms a physical and functional complex with RAB6. Our results point to a role of COH1 as a RAB6 effector protein. Depletion of COH1 leads to decreased neurite outgrowth in cultured primary hippocampal neurons. These results establish a critical role for RAB6-dependent function of COH1 in neuritogenesis by regulating Golgi complex organization. |
|
| Publications: |
1 |
Organism: |
Rattus Norvegicus |
3.0
VPS13B
- 
- 