Summary
Name | FBXO30 |
Full Name | F-box only protein 30 |
Synonyms | FBX30_HUMAN | FBX30 |
Primary ID | Q8TB52 |
Links | - - |
Type | protein |
Relations | 2 |
Pathways | Myofiber: BMP |
Function | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Required for muscle atrophy following denervation. |
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Relations
Regulator | Mechanism | target | score ℹ | |
---|---|---|---|---|
+ | FBXO30 | up-regulates | Muscle_atrophy | 0.7 |
Publications: | 1 | Organism: | Mus Musculus | |
Tissue: | Muscle | |||
+ | SMAD1/5/8/SMAD4 | down-regulates | FBXO30 | 0.2 |
Publications: | 1 | Organism: | Mus Musculus | |
Tissue: | Muscle | |||