Summary

Name PHIP
Full Name PH-interacting protein
Synonyms PHIP, IRS-1 PH domain-binding protein, WD repeat-containing protein 11 | WDR11
Primary ID Q8WWQ0
Links - -
Type protein
Relations 2
Function Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding Cullin4-RBX1-DDB1 0.334
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding IRS1 0.531
Publications: 1 Organism: Chlorocebus Aethiops