Summary

Name RAMAC
Full Name RNA guanine-N7 methyltransferase activating subunit
Synonyms Protein FAM103A1, RNA guanine-7 methyltransferase activating subunit, RNMT-activating mRNA cap methyltransferase subunit, RNMT-activating mini protein, RAM | C15orf18, FAM103A1, RAMMET
Primary ID Q9BTL3
Links - -
Type protein
Relations 1
Pathways mRNA maturation
Function Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs (PubMed:22099306, PubMed:27422871). Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT (PubMed:27422871). Regulates RNMT expression by a post-transcriptional stabilizing mechanism (PubMed:22099306). Binds RNA (PubMed:22099306).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding RNMT 0.2
Publications: 1 Organism: Homo Sapiens
Pathways:mRNA maturation, mRNA maturation