3.0
Summary
| Name |  FANCIView Modifications |
| Full Name | Fanconi anemia group I protein |
| Synonyms | Protein FACI | KIAA1794 |
| Primary ID | Q9NVI1 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Function | Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | ATM |
phosphorylation
|
FANCI | 0.526 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Fanconi anemia core complex | up-regulates activity 
ubiquitination
|
FANCI | 0.698 |
| Publications: | 1 | |||
| + | FANCL | up-regulates activity
ubiquitination
|
FANCI | 0.842 |
| Publications: | 1 | |||
| + | USP1 | down-regulates activity 
deubiquitination
|
FANCI | 0.663 |
| Publications: | 1 | |||
| + | FANCI | form complex 
binding
|
Fanconi anemia ID complex | 0.956 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | ATR | up-regulates activity
phosphorylation
|
FANCI | 0.621 |
| Publications: | 1 | Organism: | Homo Sapiens | |