| + |
HDAC2 | form complex 
binding
|
MECP2/SIN3A/HDAC complex |
0.71 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267736 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 9620804 |
We show that a region of MeCP2 that localizes with the TRD associates with a corepressor complex containing the transcriptional repressor mSin3A and histone deacetylases. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MECP2/SIN3A/HDAC complex | down-regulates quantity by repression 
transcriptional regulation
|
BDNF |
0.38 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265071 |
|
|
Mus musculus |
Cerebral Cortical Neuron |
| pmid |
sentence |
| 14593184 |
Moreover, increased Bdnf transcription involves dissociation of the MeCP2–histone deacetylase–mSin3A repression complex from its promoter. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| Pathways: | Rett syndrome |
| + |
SIN3A | form complex
binding
|
MECP2/SIN3A/HDAC complex |
0.825 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267737 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 9620804 |
We show that a region of MeCP2 that localizes with the TRD associates with a corepressor complex containing the transcriptional repressor mSin3A and histone deacetylases. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MECP2 | form complex
binding
|
MECP2/SIN3A/HDAC complex |
0.689 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265070 |
|
|
Rattus norvegicus |
|
| pmid |
sentence |
| 9620804 |
We show that a region of MeCP2 that localizes with the TRD associates with a corepressor complex containing the transcriptional repressor mSin3A and histone deacetylases. |
|
| Publications: |
1 |
Organism: |
Rattus Norvegicus |
| Pathways: | Rett syndrome |
| + |
HDAC1 | form complex
binding
|
MECP2/SIN3A/HDAC complex |
0.743 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267738 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 9620804 |
We show that a region of MeCP2 that localizes with the TRD associates with a corepressor complex containing the transcriptional repressor mSin3A and histone deacetylases. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
MECP2/SIN3A/HDAC complex