| + |
TFIIIB | up-regulates activity 
binding
|
RNA Polymerase III |
0.64 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266181 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9308965 |
Transcription by RNA polymerase III (Pol III) requires multiple general initiation factors that, in isolated form, assemble onto the promoter in an ordered fashion. Here, it is shown that all components required for transcription of the VA1 and tRNA genes, including TFIIIB, TFIIIC, and RNA Pol III, can be coimmunopurified from a HeLa cell line that constantly expresses a FLAG epitope-tagged subunit of human RNA Pol III. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Transcription initiation |
| + |
BRF1 | form complex 
binding
|
TFIIIB |
0.701 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266190 |
|
|
|
|
| pmid |
sentence |
| 29378333 |
Both in yeast and mammalian cells, TFIIIB consists of three subunits: TFIIB-related Brf1, TATA-box binding protein (TBP), common also for the other two RNA polymerases, and Pol III-specific subunit, Bdp1 (Table 1). |
|
| Publications: |
1 |
| + |
GTF3A | up-regulates activity
relocalization
|
TFIIIB |
0.523 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269309 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 8907699 |
One of the major functions of TFIIIA is to program the 5S RNA gene for transcription by binding directly to the ICR, which subsequently directs an ordered assembly of general factors to form a functional transcription complex. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TBP | form complex
binding
|
TFIIIB |
0.827 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266192 |
|
|
|
|
| pmid |
sentence |
| 29378333 |
Both in yeast and mammalian cells, TFIIIB consists of three subunits: TFIIB-related Brf1, TATA-box binding protein (TBP), common also for the other two RNA polymerases, and Pol III-specific subunit, Bdp1 (Table 1). |
|
| Publications: |
1 |
| + |
BDP1 | form complex
binding
|
TFIIIB |
0.878 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266189 |
|
|
|
|
| pmid |
sentence |
| 29378333 |
Both in yeast and mammalian cells, TFIIIB consists of three subunits: TFIIB-related Brf1, TATA-box binding protein (TBP), common also for the other two RNA polymerases, and Pol III-specific subunit, Bdp1 (Table 1). |
|
| Publications: |
1 |
| + |
BRF2 | form complex
binding
|
TFIIIB |
0.71 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266191 |
|
|
|
|
| pmid |
sentence |
| 29378333 |
Both in yeast and mammalian cells, TFIIIB consists of three subunits: TFIIB-related Brf1, TATA-box binding protein (TBP), common also for the other two RNA polymerases, and Pol III-specific subunit, Bdp1 (Table 1). |
|
| Publications: |
1 |
3.0
TFIIIB