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Acknowledgements
User-Defined List
Legend:
Not in Signor
In Signor
RAF1
BRAF
EPHA2
PTPN11
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Click on any node or edge to view details about them
Toolbox
complexity level
ℹ
level 1
connect
level 2
first neighbors
level 3
all
Include physical interactions (score>0.4)
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Searched Entities (4 found)
BRAF
P15056
protein
cancer census
EPHA2
P29317
protein
cancer census
PTPN11
Q06124
protein
cancer census
RAF1
P04049
protein
cancer census
overlap with cancer modules
press row to view shared entities
mTOR in cancer
(1/15)
Shared Entities:
AKT
FLT3 in AML
(7/40)
Shared Entities:
AKT
ERK1/2
MEK1/2
PTPN11
BRAF
JAK2
KRAS
NPM1_new
(6/24)
Shared Entities:
AKT
ERK1/2
MEK1/2
PTPN11
BRAF
NRAS
HaematopoiesisTranscriptionalControl
(1/17)
Shared Entities:
HRAS
AML1-ETO in AML
(1/18)
Shared Entities:
JAK2
KIT in AML
(7/30)
Shared Entities:
AKT
ERK1/2
MEK1/2
PTPN11
BRAF
JAK2
NRAS
miRNA in AML
(1/35)
Shared Entities:
AKT
BCR-ABL in AML
(6/20)
Shared Entities:
AKT
ERK1/2
MEK1/2
BRAF
JAK2
KRAS
ASXL1 in AML
(1/13)
Shared Entities:
AKT
ErbB receptors in cancer
(5/12)
Shared Entities:
AKT
HRAS
ERK1/2
MEK1/2
BRAF
RTKs in cancer
(5/12)
Shared Entities:
AKT
HRAS
ERK1/2
MEK1/2
BRAF
WNT/FLT3
(3/27)
Shared Entities:
AKT
ERK1/2
PRKACA
Triple mutant AML
(2/18)
Shared Entities:
AKT
ERK1/2
FLT3-ITD signaling
(7/70)
Shared Entities:
AKT
AKT1
ERK1/2
MEK1/2
PTPN11
BRAF
KRAS
AML_TRIPLETS
(6/22)
Shared Entities:
AKT
ERK1/2
MEK1/2
PTPN11
BRAF
NRAS
Onco-fusion proteins in AML
(2/27)
Shared Entities:
JAK2
NRAS
FLT3-ITD in AML
(2/37)
Shared Entities:
AKT
ERK1/2
all cancer modules
(11/258)
Clear selection
gene enrichment analysis
(note: analysis will be performed for input proteins and up to 50 total proteins, the non-input ones being randomly selected)
ℹ
Cancer Modules
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Cancer Module
Hits
p-value