3.0
Eosinophil: CCR1
Pathway ID: SIGNOR-EosCCR1
Description: CCR1 is a member of the beta chemokine receptor family, a seven transmembrane protein similar to G protein-coupled receptors. The most important ligands for this receptor are macrophage inflammatory protein 1 alpha (MIP-1 alpha or CCL3), RANTES (CCL5) and monocyte chemoattractant protein 3 (MCP-3 or CCL7). The signaling pathway mediated by this receptor and chemokines is crucial for the recruitment of effector immune cells to the site of inflammation.
Curated by: Alessandro Palma
Description: CCR1 is a member of the beta chemokine receptor family, a seven transmembrane protein similar to G protein-coupled receptors. The most important ligands for this receptor are macrophage inflammatory protein 1 alpha (MIP-1 alpha or CCL3), RANTES (CCL5) and monocyte chemoattractant protein 3 (MCP-3 or CCL7). The signaling pathway mediated by this receptor and chemokines is crucial for the recruitment of effector immune cells to the site of inflammation.
Curated by: Alessandro Palma
