3.0
Summary
| Name |  SH3PXD2BView Modifications |
| Full Name | SH3 and PX domain-containing protein 2B |
| Synonyms | Adapter protein HOFI, Factor for adipocyte differentiation 49, Tyrosine kinase substrate with four SH3 domains | FAD49, KIAA1295, TKS4 |
| Primary ID | A1X283 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation (By similarity). |
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phosphorylation