Relation Results

Summary

Name ethanol
Synonyms 1-hydroxyethane (ChemIDplus), [CH2Me(OH)] (MolBase), [OEtH] (MolBase), alcohol (NIST Chemistry WebBook), alcohol etilico (ChEBI), alcool ethylique (ChemIDplus), Alkohol (ChemIDplus), Aethanol (ChemIDplus), Aethylalkohol (ChemIDplus), C2H5OH (ChEBI), Dehydrated ethanol (KEGG DRUG), etanol (ChEBI), Ethanol (KEGG COMPOUND), ETHANOL (PDBeChem), ethanol (UniProt), ethanol (ChEBI), Ethyl alcohol (KEGG COMPOUND), EtOH (ChemIDplus), hydroxyethane (ChemIDplus), Methylcarbinol (KEGG COMPOUND), spiritus vini (ChEBI)
IUPAC ethanol
Formula C2H6O
PRIMARY ID
(Read more)		 CHEBI:16236
Type chemical
Relations 5

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Type: Score: Layout: SPV 
0.80.80.80.8ethanolGlyRGLRA1GLRA2SLC44A2

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Relations
Regulator
Mechanism
target
score ℹ
+ ethanolup-regulates activity img/direct-activation.png chemical activation GlyR 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-267794 Xenopus laevis Oocyte
pmid sentence
Pharmacologically relevant concentrations of ethanol (10-200 mM) reversibly potentiated the glycine receptor function in all receptors. Ethanol potentiation depended on the glycine concentration used, with decreased potentiation observed at higher glycine concentrations.
Identifier Residue Sequence Organism Cell Line
SIGNOR-270260 Xenopus laevis Oocyte
pmid sentence
Pharmacologically relevant concentrations of ethanol (10-200 mM) reversibly potentiated the glycine receptor function in all receptors. Ethanol potentiation depended on the glycine concentration used, with decreased potentiation observed at higher glycine concentrations.
Publications: 2 Organism: Xenopus Laevis
+ ethanolup-regulates activity img/direct-activation.png chemical activation GLRA1 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-258495 Xenopus laevis Oocyte
pmid sentence
Pharmacologically relevant concentrations of ethanol (10-200 mM) reversibly potentiated the glycine receptor function in all receptors. Ethanol potentiation depended on the glycine concentration used, with decreased potentiation observed at higher glycine concentrations.
Publications: 1 Organism: Xenopus Laevis
+ ethanolup-regulates activity img/direct-activation.png chemical activation GLRA2 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-258496 Xenopus laevis Oocyte
pmid sentence
Pharmacologically relevant concentrations of ethanol (10-200 mM) reversibly potentiated the glycine receptor function in all receptors. Ethanol potentiation depended on the glycine concentration used, with decreased potentiation observed at higher glycine concentrations.
Publications: 1 Organism: Xenopus Laevis
+ ethanolup-regulates quantity img/indirect-activation.png SLC44A2 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-260407 Homo sapiens VA13-TS4 Cell
pmid sentence
Among these, SLC44A2 (a putative choline transporter) was strikingly upregulated by ethanol (three fold), and GCN5 silencing downregulated it
Publications: 1 Organism: Homo Sapiens
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