| + |
cytidine | up-regulates quantity 
precursor of
|
cytidine 5'-monophosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275857 |
|
|
|
|
| pmid |
sentence |
| 11306702 |
Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases.|We have cloned the cDNA of two human UCKs. The approximately 30-kDa proteins, named UCK1 and UCK2, were expressed in Escherichia coli and shown to catalyze the phosphorylation of Urd and Cyd. The enzymes did not phosphorylate deoxyribonucleosides or purine ribonucleosides. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280593 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35583288 |
Uridine-cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein with high sequence similarity to other uridine-cytidine kinases (UCKs). UCKs play an important role in the pyrimidine salvage pathway, catalyzing the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280601 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27239701 |
Uridine-cytidine kinase (UCK) is a pyrimidine ribonucleoside kinase that catalyses the first step of the pyrimidine salvage pathway, the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280609 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27239701 |
Uridine-cytidine kinase (UCK) is a pyrimidine ribonucleoside kinase that catalyses the first step of the pyrimidine salvage pathway, the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280565 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20637175 |
Human deoxycytidine kinase (dCK4; EC 2.7.1.74) catalyzes the phosphorylation of 2′-deoxycytidine (dCyd), 2′-deoxyadenosine and 2′-deoxyguanosine to their corresponding monophosphate forms, using ATP or UTP as phosphoryl donors. This reaction is the first and rate-limiting step of the deoxyribonucleoside salvage pathway, which provides deoxynucleoside triphosphates for DNA replication and repair as an alternative to de novo nucleotide synthesis |
|
| Publications: |
5 |
Organism: |
, Homo Sapiens |
| + |
UCKL1 | down-regulates quantity 
chemical modification
|
cytidine |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280591 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35583288 |
Uridine-cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein with high sequence similarity to other uridine-cytidine kinases (UCKs). UCKs play an important role in the pyrimidine salvage pathway, catalyzing the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UCK1 | down-regulates quantity
chemical modification
|
cytidine |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280599 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27239701 |
Uridine-cytidine kinase (UCK) is a pyrimidine ribonucleoside kinase that catalyses the first step of the pyrimidine salvage pathway, the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UCK2 | down-regulates quantity
chemical modification
|
cytidine |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280607 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27239701 |
Uridine-cytidine kinase (UCK) is a pyrimidine ribonucleoside kinase that catalyses the first step of the pyrimidine salvage pathway, the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
DCK | down-regulates quantity
chemical modification
|
cytidine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280563 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20637175 |
Human deoxycytidine kinase (dCK4; EC 2.7.1.74) catalyzes the phosphorylation of 2′-deoxycytidine (dCyd), 2′-deoxyadenosine and 2′-deoxyguanosine to their corresponding monophosphate forms, using ATP or UTP as phosphoryl donors. This reaction is the first and rate-limiting step of the deoxyribonucleoside salvage pathway, which provides deoxynucleoside triphosphates for DNA replication and repair as an alternative to de novo nucleotide synthesis |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
cytidine