4.0
Summary
| Name |  bosutinib
|
| Synonyms | 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile (ChemIDplus), Bosutinib (KEGG DRUG), SKI 606 (ChemIDplus), SKI-606 (ChemIDplus) |
| IUPAC | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile |
| Formula | C26H29Cl2N5O3 |
| PRIMARY ID (Read more) |
CHEBI:39112 |
| Type | chemical |
| Relations | 5 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | bosutinib | down-regulates activity 
chemical inhibition
|
ABL1 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | bosutinib | down-regulates
chemical inhibition
|
ABL1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | bosutinib | down-regulates activity
chemical inhibition
|
SRC | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | bosutinib | down-regulates activity
chemical inhibition
|
BCR-ABL | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | bosutinib | down-regulates
chemical inhibition
|
SRC | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |