+ |
3-[1-[[4-(7-phenyl-3H-imidazo[4,5-g]quinoxalin-6-yl)phenyl]methyl]-4-piperidinyl]-1H-benzimidazol-2-one | down-regulates activity
chemical inhibition
|
AKT1 |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262010 |
|
|
|
|
pmid |
sentence |
25309440 |
Different agents were used to inhibit either the PI3K/Akt or MEK/ERK pathways. The PI3K inhibitor, LY294002, and the Akt inhibitor, Akt inhibitor VIII, were used to inhibit the PI3K/Akt pathway. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262227 |
|
|
Homo sapiens |
T-lymphocyte |
pmid |
sentence |
25336630 |
stimulations were performed in the presence or absence of Akt inhibitor VIII, which selectively inhibits Akt1/Akt2 activity. |
|
Publications: |
2 |
Organism: |
, Homo Sapiens |
+ |
3-[1-[[4-(7-phenyl-3H-imidazo[4,5-g]quinoxalin-6-yl)phenyl]methyl]-4-piperidinyl]-1H-benzimidazol-2-one | down-regulates activity
chemical inhibition
|
AKT |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-269849 |
|
|
|
|
pmid |
sentence |
25309440 |
Different agents were used to inhibit either the PI3K/Akt or MEK/ERK pathways. The PI3K inhibitor, LY294002, and the Akt inhibitor, Akt inhibitor VIII, were used to inhibit the PI3K/Akt pathway. |
|
Publications: |
1 |
+ |
3-[1-[[4-(7-phenyl-3H-imidazo[4,5-g]quinoxalin-6-yl)phenyl]methyl]-4-piperidinyl]-1H-benzimidazol-2-one | down-regulates activity
chemical inhibition
|
AKT2 |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262228 |
|
|
Homo sapiens |
T-lymphocyte |
pmid |
sentence |
25336630 |
stimulations were performed in the presence or absence of Akt inhibitor VIII, which selectively inhibits Akt1/Akt2 activity. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262011 |
|
|
|
|
pmid |
sentence |
25309440 |
Different agents were used to inhibit either the PI3K/Akt or MEK/ERK pathways. The PI3K inhibitor, LY294002, and the Akt inhibitor, Akt inhibitor VIII, were used to inhibit the PI3K/Akt pathway. |
|
Publications: |
2 |
Organism: |
Homo Sapiens, |
+ |
3-[1-[[4-(7-phenyl-3H-imidazo[4,5-g]quinoxalin-6-yl)phenyl]methyl]-4-piperidinyl]-1H-benzimidazol-2-one | down-regulates activity
chemical inhibition
|
AKT3 |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262012 |
|
|
|
|
pmid |
sentence |
25309440 |
Different agents were used to inhibit either the PI3K/Akt or MEK/ERK pathways. The PI3K inhibitor, LY294002, and the Akt inhibitor, Akt inhibitor VIII, were used to inhibit the PI3K/Akt pathway. |
|
Publications: |
1 |