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Summary
Name
NFKBIE
Full Name
NF-kappa-B inhibitor epsilon
Synonyms
NF-kappa-BIE, I-kappa-B-epsilon, IkB-E, IkB-epsilon, IkappaBepsilon | IKBE
Primary ID
O00221
Links
-
-
Type
protein
Relations
2
Function
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.
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by mechanism
none
binding
by effect
none
down-regulates
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
leukemia cell
Relations
Regulator
Mechanism
target
score
ℹ
+
NFKBIE
down-regulates
binding
NfKb-p65/p50
0.571
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-217361
Homo sapiens
Leukemia Cell
pmid
sentence
12835716
Nf-kb is normally sequestered in the cell cytoplasm by binding to ikbx, ikbb, ikbe
Publications:
1
Organism:
Homo Sapiens
+
NFKBIE
down-regulates
binding
NFKB1
0.52
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-102774
Homo sapiens
Leukemia Cell
pmid
sentence
12835716
Nf-kb is normally sequestered in the cell cytoplasm by binding to ikbx, ikbb, ikbe
Publications:
1
Organism:
Homo Sapiens