3.0
Summary
| Name |  MFNG
|
| Full Name | Beta-1,3-N-acetylglucosaminyltransferase manic fringe |
| Synonyms | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| Primary ID | O00587 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PubMed:10935626). Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity). |
binding