Summary

Name PIK3C2B
Full Name Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
Synonyms PI3K-C2-beta, PtdIns-3-kinase C2 subunit beta, C2-PI3K, Phosphoinositide 3-kinase-C2-beta
Primary ID O00750
Links - -
Type protein
Relations 4
Inhibitors PI-103; CH5132799
Function Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns (PubMed:10805725, PubMed:9830063, PubMed:11533253). Does not phosphorylate PtdIns(4,5)P2 (PubMed:9830063). May be involved in EGF and PDGF signaling cascades (PubMed:10805725).

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Relations

Regulator Mechanism target score ℹ
+ TRIM27down-regulates img/direct_inhibition.png ubiquitination PIK3C2B 0.401
Publications: 1 Organism: Homo Sapiens
+ PI-103down-regulates img/direct_inhibition.png chemical inhibition PIK3C2B 0.8
Publications: 1 Organism: Homo Sapiens
+ CH5132799down-regulates img/direct_inhibition.png chemical inhibition PIK3C2B 0.8
Publications: 1 Organism: Homo Sapiens
+ EGFRup-regulates img/direct-activation.png phosphorylation PIK3C2B 0.439
Publications: 1 Organism: Homo Sapiens